Right middle cerebral artery infarct after minor head trauma in an infant: Case report and literature review.

Ishaemic stroke (IS) in the paediatric population is extremely rare. In this age group, the occurrence of IS often concurs with underlying congenital heart disease, haematological, metabolic or immunological conditions. In contrast, the association between IS and minor head injury in children has been sparse in current literature. The authors report a case of a healthy 9-month-old male who was found to have a right middle cerebral artery territory infarct after a minor head injury. An extensive medical workup was performed, and it was negative for any previously undiagnosed co-morbidities. Given the paucity of such cases, the condition and its management are discussed in corroboration with current literature.

Characterization of Pyramidal Tract Shift in High-Grade Glioma Resection.

OBJECTIVE: This study aimed to characterize pyramidal tract shift in different regions of the brain during glioma resection and its association with head position and tumor location. METHODS: From 2008-2013, 14 patients presenting at the National Neuroscience Institute with high-grade glioma (World Health Organization III or IV) underwent preoperative and intraoperative diffusion tensor imaging. A novel method of placing landmarks along the preoperative and intraoperative tracts, with anterior commissure as the origin, was used to determine pyramidal tract shift. Shift was evaluated in x (lateromedial), y (anteroposterior), and z (craniocaudal) directions for 3 brain regions: brainstem, around third and lateral ventricles, and above ventricles. Shift radius is calculated as the distance between preoperative and postoperative landmarks. RESULTS: Mean shift radius was 2.72 ± 0.55, 2.98 ± 0.53, and 4.04 ± 0.58 mm at the brainstem, third and lateral ventricles, and above the ventricles, respectively (P < 0.001). Only shift in the y direction (P < 0.03) and shift radius (P < 0.03) were significantly different among regions. Head position during surgery strongly influenced shift radius above the ventricles (P < 0.005), but tumor location had no significant effect. The z-direction shift did not differ significantly among regions. CONCLUSION: Direction of pyramidal tract shift in 3 dimensions is unpredictable; hence shift radius is a more clinical useful concept. Shift radius was largest above the ventricles and was strongly influenced by head position, with a trend for temporal lobe tumors to exhibit larger shifts.